Table 3.
Relationship between the incidence of the primary endpoint and the AIP expressed as a categorical variable
| Variables | Univariate analysis HR (95% CI) |
P-value | Multivariate analysis HR (95% CI) |
P-value |
|---|---|---|---|---|
| AIP quartiles | ||||
| Q1 | Reference | Reference | ||
| Q2 | 1.376 (0.878–2.156) | 0.164 | 1.167 (0.733–1.857) | 0.516 |
| Q3 | 1.710 (1.109–2.636) | 0.015 | 1.570 (0.995–2.478) | 0.053 |
| Q4 | 2.265 (1.491–3.440) | < 0.001 | 2.249 (1.438–3.517) | < 0.001 |
| Age | 1.005 (0.991–1.019) | 0.472 | 0.996 (0.980–1.012) | 0.642 |
| BMI | 0.959 (0.916–1.005) | 0.078 | 0.922 (0.876–0.970) | 0.002 |
| Hypertension | 1.068 (0.789–1.447) | 0.669 | 1.241 (0.890–1.729) | 0.203 |
| Previous MI | 1.492 (1.095–2.033) | 0.011 | 0.781 (0.532–1.145) | 0.205 |
| Past PCI | 1.723 (1.285–2.310) | < 0.001 | 1.263 (0.734–2.080) | 0.425 |
| PAD | 2.511 (1.836–3.435) | < 0.001 | 1.717 (1.192–2.473) | 0.004 |
| Cardiac failure | 1.951 (1.308–2.909) | 0.001 | 1.165 (0.677–2.004) | 0.581 |
| LVEF | 0.974 (0.959–0.990) | 0.002 | 0.983 (0.962–1.004) | 0.120 |
| SCr | 1.013 (1.006–1.021) | 0.001 | 1.010 (1.002–1.019) | 0.014 |
| LDL-C | 1.078 (0.916–1.269) | 0.366 | 1.028 (0.852–1.239) | 0.774 |
| FPG | 1.201 (1.132–1.274) | < 0.001 | 1.156 (1.087–1.230) | < 0.001 |
| Clinical presentation | ||||
| UAP | Reference | Reference | ||
| NSTEMI | 0.677 (0.416–1.102) | 0.117 | 0.467 (0.275–0.792) | 0.005 |
| STEMI | 1.098 (0.690–1.747) | 0.695 | 0.850 (0.508–1.424) | 0.538 |
| CAD severity | ||||
| One-vessel disease | Reference | Reference | ||
| Two-vessel disease | 1.756 (0.809–3.810) | 0.154 | 1.230 (0.549–2.755) | 0.615 |
| LM/three-vessel disease | 3.541 (1.740–7.205) | < 0.001 | 1.823 (0.858–3.873) | 0.118 |
| Restenotic lesions | 2.290 (1.658–3.163) | < 0.001 | 1.667 (0.914–3.040) | 0.095 |
| Lesions > 20 mm long | 1.984 (1.461–2.695) | < 0.001 | 1.566 (1.129–2.174) | 0.007 |
| DCB use | 1.913 (1.228–2.980) | 0.004 | 0.990 (0.571–1.715) | 0.970 |
| Complete revascularization | 0.467 (0.352–0.619) | < 0.001 | 0.687 (0.504–0.936) | 0.017 |
| Insulin at discharge | 1.396 (1.051–1.854) | 0.021 | 1.056 (0.775–1.438) | 0.730 |