Table 2. Effect of P1 Amino Acid Modificationa.
| reagent | 4 | 5 | 6 | 7 |
|---|---|---|---|---|
| cathepsin B | 100 | 5 | 20 (4 h) | 0 |
| human serum | 0 | 0 | 0 | 0 |
| mouse serum | 100 | 72 | 100 | 70 |
a
Values shown are % drug release from the NAC derivative in 24 h.
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