Table 7. Stability of m-Amide Linker–Payloadsa.
| reagent | 17 | 18 |
|---|---|---|
| cathepsin B | 100 | 100 |
| human serum | 0 | 0 |
| mouse serum | 3 | 6 |
a
Values shown are % drug release from the linker–payload in 24 h.
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