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. 2020 Sep 29;11(11):2268–2276. doi: 10.1021/acsmedchemlett.0c00395

Table 3. Antiproliferative Activities of Compounds 6a–b and 6h–j against KYSE520, OE33, Ca9-22, TR-146, and U266B Cell Lines after 48–72 h of Drug Treatment.

IC50 (μM)a
compd KYSE520 OE33 Ca9-22 TR-146 U266B
6a 197 17.73 >1000 >1000  
6b 12.76 5.56 19 18  
6c     >1000 >1000  
6h 33.81 13.82 >1000 54  
6i     55 >1000 59.38
6j   37.83 >1000 133 20.25
a

Each value is the mean of at least three determinations.