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. 2020 Nov 16;11:484. doi: 10.1186/s13287-020-01996-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Forest plots showing daily insulin requirement before and after application of umbilical cord-derived stem cell transplantation. a Comparison of daily insulin requirement at baseline and after WJ-MSCs intervention in both T1DM and T2DM and b comparison of daily insulin requirement at baseline and after UCB intervention in both T1DM and T2DM. The random-effects meta-analysis model (Der Simonian−Laird method) was used. The ends of the horizontal bars denote a 95% CI. The diamond gives the overall standardized mean difference (pooled estimate) for the combined results of all included trials