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| IC50 (μM) | TM-P2-Thal | TM-P4-Thal | TM |
|---|---|---|---|
| SIRT1 | 37 ± 3.5 | 41 ± 5.1 | >83 |
| SIRT2 Deacetylase (with preincubation) | 0.069 ± 0.032 | 0.078 ± 0.018 | 0.093 ± 0.012 |
| SIRT2 Deacetylase (without preincubation) | 0.12 ± 0.020 | 0.093 ± 0.025 | 0.15 ± 0.036 |
| SIRT2 Defatty-acylase (with preincubation) | 0.17 ± 0.044 | 0.11 ± 0.063 | 0.37 ± 0.031 |
| SIRT2 Defatty-acylase (without preincubation) | >83 | >83 | >83 |
| SIRT3 | >83 | >83 | >83 |
| SIRT5 | >83 | >83 | >83 |
| SIRT6 | >83 | >83 | >83 |
