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. 2020 Oct 5;11(11):2232–2237. doi: 10.1021/acsmedchemlett.0c00359

Table 1. IC50 Values (μM) of Corilagin and TGG in Antioxidant Assaysa.

Assays Corilagin TGG Trolox
Fe2+-chelation 7 ± 1a 11 ± 4b 14 ± 2b, *
PTIO-scavenging (pH 7.4) 94 ± 8a 115 ± 11b 445 ± 35c
PTIO-scavenging (pH 4.5) 204 ± 13a 290 ± 35b 289 ± 27b
FRAP 12 ± 1a 35 ± 2b 81 ± 2c
DPPH-scavenging 1 ± 0a 1 ± 0a 7 ± 0b
a

The IC50 value (in μM unit) was defined as the final concentration of 50% radical inhibition or relative reducing/chelating power, which was calculated via linear regression analysis (Figures S12–16, Supporting Information) and expressed as the mean ± SD (n = 3). The linear regression was analyzed by the Origin 2017 professional software. The IC50 values with different superscripts (a, b, or c) in the same row, differ significantly (p < 0.05). Trolox is the positive control (*denotes that the positive control is sodium citrate instead of Trolox). PTIO, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide radical; FRAP, Fe3+-reducing antioxidant power; DPPH, 1,1-diphenyl-2-picrylhydrazyl radical.