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. 2020 Sep 24;11(11):2244–2252. doi: 10.1021/acsmedchemlett.0c00387

Table 2. Evaluation of Azaindole C3 Substituents.

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a

Enzymatic kinase activity assay.

b

Ratio of PI3Kα or PI3Kδ enzymatic inhibition over PI3Kγ inhibition.

c

Determined using the AlphaLISA SureFire Ultra Akt assay (PerkinElmer) with THP-1 cells.

d

Racemate.

e

Compound was tested once.