Table 5. Further Characterization and SAR of C3 Benzoic Acid and Phenylacetic Acid Azaindole Derivatives.
Enzymatic kinase activity assay.
Ratio of PI3Kα or PI3Kδ enzymatic inhibition over PI3Kγ inhibition.
Cellular potency in THP-1 cell line.
Compound was tested once.
n.d. = value not determined.