Table 1.
Clinical Characteristics of All Participants
| Characteristic | CHP (n = 82) | IPF (n = 103) | Control (n = 103) | P Value |
|---|---|---|---|---|
| Age, yr | 59.4 ± 10.6 | 60.3 ± 8.3 | 59.9 ± 10.2 | 0.98 |
| Sex | n = 81 | n = 103 | n = 103 | 0.23 |
| M | 38 (47) | 57 (55) | 45 (44) | |
| F | 43 (53) | 46 (45) | 58 (56) | |
| Race | n = 75 | n = 101 | n = 103 | |
| Non-Hispanic white | 59 (79) | 85 (84) | 87 (84) | 0.055 |
| Hispanic | 10 (13) | 7 (7) | 4 (4) | — |
| Asian | 4 (5) | 2 (2) | 3 (3) | — |
| Black | 1 (1) | 4 (4) | 9 (9) | — |
| Other | 1 (1) | 3 (3) | 0 (0) | — |
| Smoke | n = 73 | n = 95 | n = 96 | 0.9 |
| Ever | 33 (45) | 40 (42) | 43 (45) | |
| Never | 40 (55) | 55 (58) | 53 (55) | |
| Sampling method | 0.51 | |||
| Surgical lung biopsy | 26 (32) | 36 (35) | 41 (40) | |
| Transplant | 56 (68) | 67 (65) | 62 (60) | |
| MUC5B genotype | <0.001 | |||
| GG | 52 (63) | 54 (52) | 80 (78) | |
| GT | 29 (35) | 43 (42) | 21 (20) | |
| TT | 1 (2) | 6 (6) | 2 (2) | |
| Minor allele frequency | 0.19 | 0.27 | 0.12 | — |
Definition of abbreviations: CHP = chronic hypersensitivity pneumonitis; IPF = idiopathic pulmonary fibrosis.
Continuous variables are shown as mean ± SD, and categorical variables are shown as n (%). P values are provided among three groups.