Table 6.
CHP-Specific Differentially Expressed Genes
| Gene Name | Base Mean | log2 Fold Change | P Value | Adjusted P Value |
|---|---|---|---|---|
| BGN | 1,607.81 | 3.43 | 3.35 × 10−24 | 1.86 × 10−21 |
| MYBL2 | 3.46 | 3.23 | 4.86 × 10−3 | 1.22 × 10−2 |
| CHIT1 | 5,195.27 | 3.09 | 2.54 × 10−11 | 5.81 × 10−14 |
| PAX5 | 6.39 | 2.94 | 1.80 × 10−7 | 1.55 × 10−6 |
| TIMP1 | 21,378.87 | 2.75 | 7.77 × 10−21 | 1.85 × 10−18 |
| PCP4 | 8.97 | 2.68 | 6.13 × 10−4 | 2.05 × 10−3 |
| TIMD4 | 15.4 | 2.6 | 1.12 × 10−4 | 4.66 × 10−4 |
| TOP2A | 70.63 | 2.13 | 6.69 × 10−7 | 5.04 × 10−6 |
| BFSP2 | 32.09 | 2.11 | 3.85 × 10−14 | 6.51 × 10−9 |
| MYBPC2 | 17.7 | 2.07 | 3.24 × 10−5 | 1.55 × 10−4 |
| C4B | 6,629.57 | 2.06 | 2.89 × 10−26 | 2.29 × 10−23 |
| CCL25 | 10.43 | 2.04 | 2.77 × 10−5 | 1.35 × 10−4 |
| TSPAN8 | 368.71 | 2.02 | 7.86 × 10−14 | 3.27 × 10−12 |
| MYL2 | 5.98 | 1.98 | 4.77 × 10−5 | 2.19 × 10−4 |
| CCL13 | 51.06 | 1.88 | 7.20 × 10−4 | 2.35 × 10−3 |
| TNFRSF17 | 11.6 | 1.82 | 3.20 × 10−3 | 8.48 × 10−3 |
| PLTP | 2,135.31 | 1.79 | 9.12 × 10−14 | 3.75 × 10−12 |
| CCL19 | 16.93 | 1.78 | 4.20 × 10−3 | 1.07 × 10−2 |
| SYN1 | 94.42 | 1.76 | 1.89 × 10−11 | 4.48 × 10−14 |
| ARMC1 | 29.4 | 1.76 | 1.44 × 10−6 | 9.91 × 10−6 |
| FOS | 7,972.61 | −1.67 | 7.24 × 10−7 | 5.39 × 10−6 |
| ARGLU1 | 1,180.58 | −1.69 | 2.77 × 10−17 | 2.89 × 10−15 |
| STC1 | 3.36 | −1.72 | 2.17 × 10−2 | 4.40 × 10−2 |
| INMT-MINDY4 | 66.96 | −1.72 | 2.42 × 10−13 | 8.99 × 10−12 |
| HBEGF | 75.02 | −1.73 | 1.62 × 10−9 | 2.36 × 10−8 |
| ADAMTS7 | 98.77 | −1.77 | 1.76 × 10−19 | 3.15 × 10−17 |
| AC142391.1 | 16.24 | −1.8 | 6.53 × 10−4 | 2.17 × 10−3 |
| SULT1E1 | 12.09 | −1.82 | 2.36 × 10−3 | 6.52 × 10−3 |
| PLEKHH2 | 319.79 | −1.83 | 3.23 × 10−16 | 2.51 × 10−14 |
| OLAH | 63.02 | −1.84 | 9.90 × 10−9 | 1.19 × 10−7 |
| CDC42EP2 | 7.92 | −1.84 | 1.83 × 10−2 | 3.81 × 10−2 |
| OLR1 | 745.23 | −1.9 | 1.23 × 10−9 | 1.85 × 10−8 |
| MGAT3 | 61.56 | −1.9 | 6.71 × 10−12 | 1.76 × 10−14 |
| CDH13 | 295.38 | −2 | 1.59 × 10−20 | 3.57 × 10−18 |
| FMO2 | 478.74 | −2.07 | 9.03 × 10−13 | 2.90 × 10−11 |
| GPD1 | 181.69 | −2.1 | 2.62 × 10−14 | 4.64 × 10−9 |
| KLF15 | 32.39 | −2.11 | 4.30 × 10−6 | 2.61 × 10−5 |
| DYTN | 2.66 | −2.36 | 5.68 × 10−4 | 1.92 × 10−3 |
| ADRA1B | 9.4 | −2.4 | 1.93 × 10−4 | 7.49 × 10−4 |
| ANO3 | 6.85 | −2.85 | 5.53 × 10−12 | 1.48 × 10−14 |
Definition of abbreviation: CHP = chronic hypersensitivity pneumonitis.
Top 20 up- and downregulated genes in CHP. The table shows genes differentially expressed in CHP but not significant in idiopathic pulmonary fibrosis. The table was sorted by log2 fold change in CHP with transplanted samples.