Figure 2.

Dynamic contrast–enhanced measures of pulmonary blood flow (PBF) stratified by biological sex. A Student’s t test was used to determine differences between term and preterm subjects by biological sex. Males born preterm exhibit significant reductions in PBF (P = 0.035) compared with term males. Females born prematurely do not exhibit any differences in any of the dynamic contrast–enhanced measures of lung perfusion. PBF (r = −0.65; P = 0.05) is moderately correlated with days in the neonatal ICU (NICU) and with total days on ventilation in males, but not in females, when correlating PBF with days in the NICU (r = 0.04; P = 0.95) and total days on ventilation (r = 0.04; P = 0.95), respectively (data not shown). *P < 0.05.