Table 2.
Comparison of Therapeutic Outcomes between EVAC and SEMS for Anastomotic Leakage
| Outcomes | Total (n=39) | EVAC (n=11) | SEMS (n=28) | p-value |
|---|---|---|---|---|
| Follow-up duration, mo | 17.0 (9.0–26.0) | 11.0 (1.0–17.0) | 19.5 (10.3–35.0) | 0.043 |
| Successful closure | 37 (94.9) | 11 (100.0) | 26 (92.9) 26 (74.3)* |
>0.999 0.089* |
| Leak-related mortality | 1 (2.6) | 0 | 1 (3.6) | >0.999 |
| Duration of therapy, day | 31.0 (15.0–46.0) | 15.0 (6.0–21.0) | 36.0 (28.0–48.0) | <0.001 |
| Stent/sponge change or replacement | 12 (30.8) | 5 (45.5) | 7 (25.0) | 0.262 |
| Weight loss after treatment, kg† | 9.0 (6.8–12.0) | 8.0 (4.0–11.0) | 9.0 (7.0–12.0) | 0.356 |
| Antibiotics use | ||||
| Antibiotics cessation | 1 (2.6) | 1 (9.1) | 0 | 0.282 |
| Antibiotics duration, day | 24.0 (16.0–36.0) | 29.0 (15.0–47.0) | 23.5 (16.3–34.5) | 0.731 |
| Antibiotics step-up | 11 (43.6) | 0 | 11 (39.3) | 0.017 |
| Antibiotics step-down | 3 (7.7) | 2 (18.2) | 1 (3.6) | 0.187 |
| Incidence rate of stricture within 1 yr | 5 (12.8) | 1 (9.1) | 4 (14.3) | >0.999 |
Data are presented as median (interquartile range) or number (%).
EVAC, endoscopic vacuum-assisted closure; SEMS, self-expandable metallic stent.
*Value when seven cases were switched from SEMS to EVAC and classified as SEMS failure; †Except one mortality case.