Table 5.

Indications for Heparin Bridging for the Temporary Discontinuation of Warfarin¹¹³

Non-valvular atrial fibrillation with a CHA2DS2-VASc score >5*

Metallic mitral valve

Prosthetic valve with atrial fibrillation

<3 Months after venous thromboembolism

Severe thrombophilia (protein C or protein S deficiency, antiphospholipid syndrome)

*CHA2DS2-VASc, congestive heart failure (1 point), hypertension (1 point), age ≥75 years (2 points), diabetes mellitus (1 point), stroke, transient ischemic attack, or thromboembolism (2 points), vascular disease (1 point), age 65–74 years (1 point), female sex (1 point).¹¹⁷,¹¹⁸