Table 3.
Clinical Outcomes between Traction-Assisted ESD and Conventional ESD of the Colorectum
| Author (year) | Traction method | Design | Cases, n (study/control) |
Tumor size, mm (study/control) |
Procedure time, min (study/control) |
En bloc resection, % (study/control) |
Complete resection, % (study/control) |
|---|---|---|---|---|---|---|---|
| Uraoka et al. (2010)36 | Double scope | Retrospective | 21/16 | 43.6/42.4* | 96/116* (p=0.18) | 100/100 | - |
| Okamoto et al. (2012)37 | Clip line (with balloon overtube) | Retrospective | 15/15 | 37.3/36.1* | 126/165* (p<0.05) | - | 93.3/86.6 |
| Ritsuno et al. (2014)38 | S-O line | RCT | 27/23 | 33.5/37.8* | 37.4/67.1* (p=0.03) | 100/95.7 (p=0.28) | - |
| Yamada et al. (2016)39 | Clip line (clip-prelooping snare) |
Retrospective | 17/123 | 32.5/33.9* | 45.6/70.1* (p=0.047) | 100/96.7 (p=1) | 100/91.1 (p=0.36) |
| Sakamoto et al. (2017)40 | PCM | Retrospective | 73/53 | 27/25† | 19/14†,‡ (p=0.03) | 100/92 (p=0.03) | 93/91 (p=0.74) |
| Mori et al. (2017)41 | Clip line (clip and ring-shaped thread) |
RCT | 21/22 | 27.3/27.6† | 80/130† (p=0.001) | - | - |
| Kanamori et al. (2017)42 | PCM | Retrospective | 47/49 | 26/30† | 77/85† (p=0.38) | 100/88 (p=0.015) | 100/84 (p=0.003) |
| Yoshida et al. (2018)43 | PCM (only for lesions with severe fibrosis) | Retrospective | 21/99 | 30.1/34.5* | 79.6/118.8* (p<0.001) | 95.2/74.7 (p=0.03) | 85.7/54.5 (p=0.04) |
| Yamasaki et al. (2018)44 | Clip line (modified) | RCT | 42/42 | 37/36†,¶ | 40/70† (p<0.001) | 100/100 | 93/98 (p=0.3) |
| Takezawa et al. (2019)45 | PCM | Retrospective | 280/263 | 35.3/35.7† | 69.5/78.7*,‡ (p=0.676) | 100/96 (p<0.001) | 91/85 (p=0.033) |
| Harada et al. (2019)46 | PCM | RCT | 46/45 | 32.5/34†,¶ | 29.5/41† (p<0.001) | 100/100 | 100/100 |
| Ye et al. (2019)47 | Magnetic beads | Retrospective§ | 13/13 | 589/628†,‖ | 21/16†,‡ (p=0.143) | 100/92.3 (p=1.0) | 100/93.2 (p=1.0) |
ESD, endoscopic submucosal dissection; RCT, randomized controlled trial; PCM, pocket creation method.
*Mean; †Median; ‡Dissection speed (mm2/min); §Propensity score matching; ‖Specimen area (mm2); ¶Specimen size.