Table 2.
Univariable and multivariable analyses of OS and PFS in the patients.
| Parameter | OS | PFS | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
| P | P | HR | 95%CI | P | P | HR | 95%CI | |
| Gender (male vs. female) |
0.642 | 0.656 | ||||||
| Age (≤52 years vs. >52 years) |
0.783 | 0.952 | ||||||
| Grade (I, II, III vs. IV) |
0.010* | 0.855 | 1.158 | 0.242–5.534 | <0.001* | 0.001* | 3.091 | 1.592–6.002 |
| IDH-1 (WT vs. MUT) |
0.036* | 0.011* | 0.029 | 0.002–0.448 | 0.393 | |||
| sPD-L1 (≤14.35 pg/ml vs. >14.35 pg/ml) |
0.008* | 0.516 | 2.231 | 0.198–25.126 | 0.027* | 0.617 | 0.737 | 0.223–2.435 |
| Ki-67 (≤27.5% vs. >27.5%) |
0.001* | 0.846 | 0.824 | 0.117–5.818 | 0.066 | 0.635 | 1.278 | 0.464–3.524 |
| Position (brain hemispheres vs. brainstem) |
0.001* | 0.002* | 26.302 | 3.239–213.550 | 0.876 | |||
| Treatment (RT vs. RT + chemotherapy ± target |
0.708 | 0.715 | ||||||
| Change in sPD-L1 (up vs. down) | 0.040* | 0.003* | 0.019 | 0.001–0.268 | 0.770 | |||
Factors with P ≤ 0.1 in univariate analysis can be included in the multivariate analysis.
OS, overall survival; PFS, progression-free survival; HR, hazard ratio; CI, confidence interval.
*P ≤ 0.05.