Table 3a.

Multivariable Cox regression analysis for overall survival of low-risk patients

	Univariate analysis			Multivariate analysis
Covariate	HR	95% CI	P-value	HR	95% CI	P-value
Age at resection	1.02	1.01-1.03	<0.001	1.02	1.01-1.03	<0.001
Right-sided tumor	1.15	0.94-1.41	0.17	1.10	0.89-1.36	0.40
Node positive primary tumor	1.18	1.02-1.38	0.03	1.40	1.19-1.65	<0.001
Disease-free interval (cont.)	1.00	1.00-1.01	0.26	0.99	0.99-1.00	0.01
Number CRLM (cont.)	1.06	1.01-1.12	0.02	1.08	1.07-1.1	0.005
Diameter CRLM (cont.)	1.09	1.07-1.12	<0.001	1.10	1.07-1.13	<0.001
Preoperative CEA (cont.)	1.00	1.00-1.00	0.007	1.00	1.00-1.00	0.03
Irradical resection (R1)	1.67	1.32-2.13	<0.001	1.58	1.22-2.03	<0.001
Additional ablation	1.17	0.82-1.66	0.39	1.34	0.90-2.01	0.15
Year of surgery	0.98	0.97-1.00	0.008	0.99	0.98-1.01	0.22
Perioperative SYS	0.95	0.81-1.11	0.51	0.99	0.82-1.19	0.90