| Haynesworth et al. (2002) |
The initial PRP contained 1,600 ×103 plt/μ L (5fold). PRP-lysates corresponding to PRP concentrations of 0.625, 1.25, and 2.5 was made by diluting the lysate in MDEM. Each concentration was added to the media in a ratio of 10%/90% (Vol/Vol) |
10% |
1.6 × 106
|
| Rughetti et al. (2008) |
Initial PRP was activated and diluted in DMEM + 2.5% FCS (proliferation) or in MDEM only (motility and invasion). Platelet concentration at 3 ×105, 5 ×105, 7.5 ×105, 1.25 ×106, 1.75 ×106, 2.25 ×106, 2.75 ×106, 3.25 ×106, 4 ×106, 5 × 106, and 7 × 106plt/ μ L was added to the medium |
Not described Probably a constant ratio |
1.25 ×106
|
| Jo et al. (2012) |
10% activated PRP was added to the culture media (Vol/Vol) at platelet concentrations of 100, 200, 400, 800, 1000, 2000, 4000, 8000 and 16,000 ×103/ μ L. |
10% |
4.0 × 106(CaC2) |
| 8.0 ×106 (CaC2 + trombine) |
| Sadoghi et al. (2013) |
1-, 5-, and 10-fold PRP was obtained by diluting initial PRP in PPP. The PRP/media ratio is unclear. |
Not described |
5-fold |
| Anitua et al. (2009) |
200% and 400% of WB baseline Appr. platelet concentration of 404 ±39 × 103 and 767 ±95 × 103 added to media in a 20%/80% ratio |
20% |
0.767 ± .95 × 106
|
| No sign. difference between PRP and controls regarding skin fibroblasts |
| Graziani et al. (2006) |
Initial PRP contained 800,000-1,37,00 plt/ μ L. Maximum PRP-lysate (PRP-max) was diluted in DMEM to obtain PRP-lysate containing 250%, 350% over WB baseline |
33% (100ul culture media and 50ul PRP-lysate of any concentration) |
2,5x ca.0.570 ×106 (osteoblast) 1x ca. 0.228 ×106 (fibroblast) |
| Mazzocca et al. (2012) |
PRPLP (382.0+/-111.6 × 103plt/ μ L) PRPDS (472.6+/-224.2 ×103 plt/ μ L) PRPHP (940.1+/-425.8 ×103 plt/ μ L) |
10% |
382.0+/-111.6 × 103 (PRPLP) - Myocytes |
| 472.6+/-224.2 × 103 ( PRPDS)- Osteoblasts |
| 382.0+/-111.6 × 103 (PRPLP) -Tenocytes |
| Berger et al. (2019) |
Platelet lysate (PL) was diluted in PPP to obtain lysates corresponding to platelet levels of 14x, 7x, 3.5x, 1.75x and 0.9x of WB. |
20% |
Young group: 0.875 ×106
|
| Old group: 3.5 ×106
|
| Wang et al. (2019) |
Platelet lysate corresponding to 0.2 ×106, 0.5 ×106, 0.8 ×106, 1.0 ×106, 1.2 ×106, 1.5 ×106, 2.0 ×106, 2.7 ×106, and 3.0 ×106
|
10% |
1.5–3.0 ×106
|
