Table 1. Characteristics of 40 patients with unresectable hepatocellular carcinoma who received lenvatinib after failure of sorafenib.
Characteristics | |
---|---|
Age (median) | 58 years (34–78) |
Body weight | 66.2 kg (44.8–109.5) |
Liver cirrhosis | 40 (100%) |
ECOG performance status | |
0 | 6 (15.0%) |
1 | 34 (85.0%) |
Sex | |
Male | 35 (87.5%) |
Female | 5 (12.5%) |
Child–Pugh classification | |
A | 31 (77.5%) |
B | 9 (22.5%) |
BCLC classification | |
B | 3 (7.5%) |
C | 37 (92.5%) |
Viral hepatitis status | |
Hepatitis B | 29 (72.5%) |
Hepatitis C | 7 (17.5%) |
No | 4 (10.0%) |
Main portal vein thrombosis | |
Yes | 11 (27.5%) |
No | 29 (72.5%) |
Macrovascular invasion | |
Yes | 19 (47.5%) |
No | 21 (52.5%) |
Hepatectomy before lenvatinib | |
Yes | 24 (60.0%) |
No | 16 (40.0%) |
Extrahepatic spread | |
Yes | 32 (80.0%) |
No | 8 (20.0%) |
AFP > 400 | |
Yes | 17 (42.5%) |
No | 23 (57.5%) |
Notes.
- ECOG
- Eastern Cooperative Oncology Group
- BCLC
- Barcelona-Clinic Liver Cancer