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. 2020 Oct 29;14:552111. doi: 10.3389/fnhum.2020.552111

Table 2.

Cerebral regions whose activity for the contrast [Landmark > Control] was predicted by navigation time across all participants and across age groups (sex and intracranial volume were included as covariates).

H BA k x y z t R2 ES [95% CI]
Multiple Regression Navigation time/[Landmark > Control]
Inferior temporal gyrus R 21 40 45 −22 −16 5.08 0.33 0.24 [0.16, 0.32]
51 −31 −13 4.80 0.28 [0.19, 0.38]
Lingual gyrus L - 27 −30 −58 5 4.69 0.14 0.40 [0.26, 0.54]
−24 −46 5 4.66 0.46 [0.30, 0.62]
Lingual gyrus R - 15 30 −49 2 4.64 0.19 0.54 [0.35, 0.73]
   [Middle temporal gyrus] 42 −49 5 3.65 0.22 [0.12, 0.32]
Middle frontal gyrus R 9 35 18 44 26 4.59 0.09 0.19 [0.13, 0.26]
Cerebellum Vermis R - 67 3 −55 −4 4.59 0.15 0.39 [0.25, 0.53]
3 −43 −13 3.92 0.40 [0.24, 0.57]
Middle temporal gyrus R 20 10 45 8 −37 4.56 0.29 0.23 [0.15, 0.32]
Parahippocampal gyrus L 19 13 −33 −40 −4 4.47 0.16 0.36 [0.23, 0.49]
Middle frontal gyrus R 10 23 15 65 20 4.37 0.09 0.65 [0.41, 0.90]
   [Superior frontal gyrus] 6 68 14 3.75 0.61 [0.34, 0.88]
Cerebellum lobule VI R - 13 27 −55 −31 4.26 0.24 0.20 [0.13, 0.28]
Superior occipital gyrus L 18 11 −21 −97 23 4.26 0.11 0.50 [0.31, 0.70]
Angular gyrus L 39 53 −54 −61 29 4.01 0.22 0.53 [0.31, 0.75]
−45 −79 35 4.00 0.37 [0.22, 0.52]
−54 −70 26 3.94 0.30 [0.18, 0.43]
Angular gyrus R 39 13 45 −58 32 4.01 0.11 0.51 [0.30, 0.72]
Superior frontal gyrus L 8 10 −9 35 47 3.97 0.13 0.22 [0.13, 0.31]
Multiple Regression Age/[Landmark > Control]
Superior temporal gyrus L 22 31 −45 −1 −16 5.61 0.26 0.16 [0.12, 0.21]
38 −51 8 −16 3.54 0.08 [0.05, 0.12]
Brainstem R - 17 3 −7 −1 5.40 0.11 0.20 [0.14, 0.26]

The statistical threshold was defined as p < 0.001 uncorrected for multiple comparisons at voxel-level with an extent voxel threshold set at 10 voxels. For each cluster, the region with the maximum t-value is listed first and other regions in the cluster are listed [in square brackets]. Montreal Neurological Institute (MNI) coordinates (x, y, z) of the peak activation and the number of voxels (k) in a cluster are also shown. All values including t-values, effect sizes, and 95% confidence intervals were provided for the peak voxel coordinate but the R2 values were provided for the entire cluster. H, hemisphere; R, right hemisphere; L, left hemisphere; BA, Brodmann area; ES, effect size; CI, confidence interval.