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. 2020 Jul 30;1(3):234–243. doi: 10.1158/2643-3230.BCD-20-0102

Table 3.

Laboratory findings in patients with multiple myeloma and COVID-19

All patients With combined adverse outcome Without combined adverse outcome
n = 100 n = 29 n = 71
Median Range n Median Range n Median Range n Reference range P
ANC 3.2 0.4–17.5 82 4.0 0.4–17.2 26 2.5 0.4–17.5 56 1.5–7.5 (×109/L) 0.025
ALC 0.6 0.1–1.8 82 0.6 0.1–1.2 26 0.7 0.1–1.8 56 0.9–3.2 (×109/L) 0.21
Platelets 152 6–507 82 119 6–350 26 164.5 19–507 56 160–400 (×109/L) 0.037
C-reactive protein 34 2.7–293 65 37 5.5–293 25 25.5 2.7–259 40 <0.50 (mg/dL) 0.25
Ferritin 658 2–40,000 64 2,015 42–40,000 25 476 2–7,174 39 22–415 (ng/mL) 0.001
D-dimer 1.3 0.2–83 59 3.0 0.3–83 24 0.9 0.2–5.5 35 <0.5 (mcg/mL FEU) 0.001
IL-6 71 6–3,238 50 102 7.3–3,238 21 64.5 6.0–532 29 <5.0 (pg/dL) 0.14

Note: Adverse combined endpoint = ICU admission, mechanical ventilation, or death. Wilcoxon rank test was used to compare laboratory values for patients who had the combined adverse outcome versus patients without the adverse outcome.

Abbreviations: ANC, absolute neutrophil count; ALC, absolute lymphocyte count; IL-6, interleukin 6.