Table 3.
Laboratory findings in patients with multiple myeloma and COVID-19
| All patients | With combined adverse outcome | Without combined adverse outcome | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| n = 100 | n = 29 | n = 71 | |||||||||
| Median | Range | n | Median | Range | n | Median | Range | n | Reference range | P | |
| ANC | 3.2 | 0.4–17.5 | 82 | 4.0 | 0.4–17.2 | 26 | 2.5 | 0.4–17.5 | 56 | 1.5–7.5 (×109/L) | 0.025 |
| ALC | 0.6 | 0.1–1.8 | 82 | 0.6 | 0.1–1.2 | 26 | 0.7 | 0.1–1.8 | 56 | 0.9–3.2 (×109/L) | 0.21 |
| Platelets | 152 | 6–507 | 82 | 119 | 6–350 | 26 | 164.5 | 19–507 | 56 | 160–400 (×109/L) | 0.037 |
| C-reactive protein | 34 | 2.7–293 | 65 | 37 | 5.5–293 | 25 | 25.5 | 2.7–259 | 40 | <0.50 (mg/dL) | 0.25 |
| Ferritin | 658 | 2–40,000 | 64 | 2,015 | 42–40,000 | 25 | 476 | 2–7,174 | 39 | 22–415 (ng/mL) | 0.001 |
| D-dimer | 1.3 | 0.2–83 | 59 | 3.0 | 0.3–83 | 24 | 0.9 | 0.2–5.5 | 35 | <0.5 (mcg/mL FEU) | 0.001 |
| IL-6 | 71 | 6–3,238 | 50 | 102 | 7.3–3,238 | 21 | 64.5 | 6.0–532 | 29 | <5.0 (pg/dL) | 0.14 |
Note: Adverse combined endpoint = ICU admission, mechanical ventilation, or death. Wilcoxon rank test was used to compare laboratory values for patients who had the combined adverse outcome versus patients without the adverse outcome.
Abbreviations: ANC, absolute neutrophil count; ALC, absolute lymphocyte count; IL-6, interleukin 6.