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. 2020 Oct 20;63(21):12873–12886. doi: 10.1021/acs.jmedchem.0c00774

Table 3. Cell Proliferation Results in Various Cancer Cell Linesa.

cell line 1 3 4 10 11 14 etoposide
DU145 15.1 ± 5.5 17.9 ± 7.4 11.1 ± 6.5 10.5 ± 6.0 8.8 ± 1.5 11.5 ± 1.3 0.5 ± 0.2
A549 19.4 ± 1.8 23.3 ± 2.3 17.8 ± 0.6 22.9 ± 6.5 18.0 ± 0.1 17.1 ± 8.7 2.4 ± 2.0
HeLa 17.0 ± 1.9 17.1 ± 3.2 21.8 ± 4.6 20.8 ± 4.5 17.2 ± 2.6 38.2 ± 9.1 1.2 ± 0.4
MCF7 13.9 ± 2.3 14.2 ± 2.5 16.2 ± 2.6 16.0 ± 0.5 15.8 ± 1.4 15.8 ± 1.3 8.9 ± 1.6
A375 9.9 ± 0.1 10.7 ± 0.1 10.8 ± 0.1 12.3 ± 1.8 15.1 ± 4.8 12.6 ± 0.7 0.5 ± 0.1
G-361 1.4 ± 0.4 1.6 ± 0.5 1.8 ± 0.6 3.0 ± 0.7 6.6 ± 3.1 8.1 ± 2.9 3.8 ± 3.0
a

A549, lung adenocarcinoma; DU145, androgen-independent prostate cancer; MCF7, breast adenocarcinoma; HeLa, cervical carcinoma; A375, human melanoma; and G-361, human melanoma. Values shown correspond to the IC50 (μM) ± SD of at least two independent experiments.