TABLE 2.
Distribution of Clinical and Laboratory Factors by Nugent BV Status Among Observations in Which the Vaginal Microbiome Is CST-IVA and CST-IVB
| CST-IVA (n = 46) | CST-IVB (n = 275) | |||
|---|---|---|---|---|
| No BV (n = 15), n (%) | BV (n = 31), n (%) | No BV (n = 142), n (%) | BV (n = 133), n (%) | |
| Reported vaginal discharge | 2 (13) | 9 (29) | 19 (3) | 24 (18) |
| Clinician-detected vaginal discharge | 8 (53) | 19 (61) | 31 (22) | 75 (56) |
| Vaginal pH >4.5 | 8 (53) | 22 (71) | 59 (42) | 106 (80) |
| Clue cells detected on wet mount | 9 (60) | 31 (100) | 43 (30) | 129 (97) |
| Whiff test positive | 8 (53) | 23 (74) | 32 (23) | 102 (77) |
| BV by Amsel’s criteria (≥3 criteria met) | 8 (53) | 23 (74) | 23 (16) | 100 (76) |
| Documented antimicrobial treatment of BV | 9 (60) | 27 (87) | 53 (37) | 120 (90) |
| Nugent score | ||||
| 0–3 | 5 (33) | 89 (63) | ||
| 4–6 | 10 (67) | 53 (37) | ||
| 7–10 | 31 (100) | 133 (100) | ||
| Alpha diversity measures, median (IQR) | ||||
| Shannon | 2.35 (1.68–2.59) | 2.34 (2.08–2.54) | 1.66 (1.21–2.07) | 2.05 (1.71–2.27) |
| Simpson | 0.87 (0.75–0.89) | 0.86 (0.80–0.89) | 0.73 (0.57–0.81) | 0.80 (0.72–0.84) |
| Richness | 26 (23–37) | 28 (25–33) | 22 (15–28) | 26 (22–31) |
| Evenness | 0.69 (0.57–0.73) | 0.70 (0.63–0.75) | 0.55 (0.44–0.63) | 0.63 (0.55–0.68) |
P values are not estimated because the purpose of this analysis is descriptive rather than inferential and because the sample size (n) represents observations rather than individuals, and thus, there are repeated observations within individual.
IQR indicates Interquartile range.