Table 3.
Univariable and multivariable survival analysis about clinical factors for ccRCC patients (OS).
| OS | |||||
| Univariable | Multivariable | ||||
| Factors | HR(95%CI) | P value | C-Index | HR(95%CI) | P value |
| Diagnosis.Age | 1.029 (1.016,1.042) | 8.48E-06 | 5.90E-01 | 1.0297 (1.007089,1.053) | .009783 |
| Sex | 0.9496 (0.698,1.292) | .742 | |||
| Ethnicity.Category | .00856 | 0.54 | 4.0689 (0.813163,20.360) | .087597 | |
| NOT HISPANIC OR LATINO VS HISPANIC OR LATINO | 4.647 (1.478,14.61) | ||||
| Race.Category | |||||
| WHITE | ref | ref | |||
| BLACK OR AFRICAN AMERICAN | 0.8848 (0.47949,1.633) | .695 | |||
| Primary.Tumor.Laterality | 7.101e-01 (0.5271,0.9566) | .0243 | 0.539 | 0.8672 (0.544495,1.381) | .54853 |
| Prior.Cancer.Diagnosis.Occurence | 1.189 (0.7729,1.83) | .43 | |||
| Tumor.Stage | 9.60E-14 | 6.67E-01 | 0.5066 (0.219945,1.167) | .110216 | |
| <T3 VS >T3 | 3.152 (2.33,4.264) | ||||
| Neoplasm.Disease.Lymph.Node | 5.56E-01 | ||||
| N0 | ref | ref | |||
| N1 | 3.5034 (1.8634,6.587) | 9.94E-05 | 0.7712 (0.174978,3.399) | .731354 | |
| NX | 0.8294 (0.6104,1.127) | 2.32E-01 | 0.8211 (0.507700,1.328) | .421734 | |
| Metastasis.Stage | 6.48E-01 | ||||
| M0 | ref | ref | |||
| M1 | 4.3730 (3.2061,5.965) | <2e-16 | 0.1237 (0.008527,1.794) | .125598 | |
| MX | 0.9321 (0.2948,2.946) | 9.05E-01 | 0.1402 (0.010157,1.936) | .142427 | |
| Neoplasm.Disease.Stage | 7.29E-01 | ||||
| stage I | ref | ref | |||
| stage II | 1.188 (0.6408,2.203) | 5.84E-01 | 0.7958 (0.307961,2.056) | .637 | |
| stage III | 2.636 (1.7616,3.944) | 2.43E-06 | 2.8863 (0.964307,8.639) | .058094 | |
| stage IV | 6.505 (4.4546,9.498) | <2e-16 | 28.2628 (1.702232,469.257) | .019751 | |
| Neoplasm.Histologic.Grade | 1.37E-07 | 6.24E-01 | .052646 | ||
| G1/2 VS G3/4 | 2.209 (1.645,2.967) | 1.7621 (0.993544,3.125) | |||
| Neoadjuvant.Therapy | .0207 | 0.512 | .62526 | ||
| YES VS NO | 2.126 (1.122,4.027) | 0.6889 (0.154382,3.074) | |||
| Hemoglobin.level | 5.83E-01 | ||||
| Normal | ref | ref | |||
| Low | 2.268 (1.591,3.232) | 5.99E-06 | 1.8912 (1.064135,3.361) | .029867 | |
| High | 5.999 (1.852,19.429) | 2.81E-03 | 8.0666 (1.772736,36.706) | .006923 | |
| Idh.level | .529 | ||||
| Normal VS High | 0.7102 (0.2447,2.062) | ||||
| Serum.calcium.level | 5.63E-01 | ||||
| Normal | ref | ref | |||
| Low | 0.7975 (0.563,1.130) | 2.03E-01 | 0.8941 (0.525870,1.520) | .67924 | |
| High | 3.8647 (1.908,7.827) | 1.74E-04 | 1.3532 (0.523101,3.500) | .53283 | |
| Platelet.count | 5.92E-01 | ||||
| Normal | ref | ref | |||
| Low | 1.649 (1.022,2.661) | 4.05E-02 | 1.2808 (0.665490,2.465) | .458799 | |
| High | 3.762 (2.491,5.682) | 3.01E-10 | 1.3250 (0.629098,2.791) | .459007 | |
| WBC | |||||
| Normal | ref | ||||
| Low | 1.7977 (0.7323,4.413) | .201 | |||
| High | 0.7651 (0.5399,1.084) | .132 | |||