TABLE 3.
Univariate and multivariate overall survival analyses of the patients
| Overall survival | |||
|---|---|---|---|
| Multivariate analysis | |||
| Variable | Univariate analysis (P value) | Hazard Ratio (95% CI) | P value |
| Age | 0.614 | Not included | |
| Gender | 0.125 | ||
| Breslow index | < 0.001 | 0.027 | |
| ≤ 2 mm | Reference | ||
| > 2‐4 mm | 1.126 (0.644‐1.9698) | 0.677 | |
| > 4 mm | 1.855 (1.080‐3.186) | 0.025 | |
| Clark level | 0.001 | 0.006 | |
| I‐III | Reference | ||
| IV‐V | 2.056 (1.189‐3.555) | ||
| Ulceration | 0.036 | 0.004 | |
| Absent | Reference | ||
| Present | 3.901 (1.262‐12.184) | ||
| No. of positive SLN | 0.003 | 0.001 | |
| 1 positive | Reference | ||
| > 1 positive | 7.755 (2.357‐27.051) | ||
| Non‐SLN status | 0.001 | 0.002 | |
| Negative | Reference | ||
| Positive | 5.974 (1.817‐16.420) | ||
| N stage | 0.002 | Not included | |
| 1a | |||
| 2a | |||
| 3a | |||
| AJCC stage* | 0.006 | Not included | |
| IIIA | |||
| IIIB | |||
| IIIC | |||
| Adjuvant therapy | 0.017 | 0.007 | |
| Yes | Reference | ||
| No | 1.924 (1.192‐3.106) | ||
*
AJCC stage refers to the pathological staging system.
Abbreviations: Non‐SLN, non‐sentinel lymph node; AJCC, American Joint Committee on Cancer.