Table 1.

Baseline demographics and clinical characteristics of 988 patients with Ewing sarcoma.

Category	All patients (n = 988)	Training cohort (n = 494)	Validation cohort (n = 494)
Mean age, yr	18.7	18.9	18.5
Age, yr
≤18	616 (62.3%)	283 (57.3%)	291 (58.9%)
>18	372 (37.7%)	211 (42.7%)	203 (41.1%)
Gender
Female	370 (37.4%)	168 (34.0%)	202 (40.9%)
Male	618 (62.6%)	326 (66.0%)	292 (59.1%)
Location
Appendicular	435 (44.0%)	216 (43.7%)	219 (44.3%)
Axial	338 (34.2%)	170 (34.4%)	168 (34.0%)
Other locations	215 (21.8%)	108 (21.9%)	107 (21.7%)
Tumor size, cm
<5	190 (19.2%)	89 (18.0%)	101 (20.4%)
5–10	499 (50.5%)	254 (51.4%)	245 (49.6%)
>10	299 (30.3%)	151 (30.6%)	148 (30.0%)
Extent of disease
Localized	264 (26.7%)	129 (26.1%)	135 (27.3%)
Regional	418 (42.3%)	211 (42.7%)	207 (41.9%)
Distant	306 (31.0%)	154 (31.2%)	152 (30.8%)
Surgical treatment
Yes	633 (64.1%)	312 (63.2%)	321 (65.0%)
No	355 (35.9%)	182 (36.8%)	173 (35.0%)
Radiation treatment
Yes	498 (50.4%)	254 (51.4%)	244 (49.4%)
No	490 (49.6%)	240 (48.6%)	250 (50.6%)
Dead
Yes	326 (33.0%)	172 (34.8%)	154 (31.2%)
No	662 (67.0%)	322 (65.5%)	340 (68.8%)