Table 3.

Multivariate analysis for OS and CSS in the training cohort (n = 494).

	OS		CSS
Variable	Hazard ratio (95% CI)	P	Hazard ratio (95% CI)	P
Age, yr
≤18	1		1
>18	1.961 (1.438–2.674)	<.001	1.863 (1.353–2.566)	<.001
Gender
Female	1	.857	1	.825
Male	0.971 (0.703–1.341)		1.039 (0.740–1.458)
Location
Appendicular	1	.193	1	.115
Axial	1.279 (0.883–1.855)	.053	1.360 (0.928–1.992)	.102
Other locations	1.528 (0.995–2.347)	.309	1.455 (0.929–2.281)	.360
Extent of disease
Localized	1	<.001	1	<.001
Regional	1.285 (0.793–2.080)	.050	1.266 (0.764–2.100)	.072
Distant	3.194 (1.981–5.149)	.004	3.413 (2.078–5.604)	.007
Tumor size, cm
<5	1	.004	1	.014
5–10	1.696 (1.000–2.878)		1.648 (0.956–2.843)
>10	2.239 (1.287–3.894)	.362	2.202 (1.247–3.888)	.337
Surgical treatment
Yes	1		1
No	1.690 (1.179–2.422)		1.588 (1.098–2.297)
Radiation treatment
Yes	1		1
No	1.164 (0.840–1.612)		1.178 (0.843–1.645)