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. 2020 Nov 13;99(46):e22391. doi: 10.1097/MD.0000000000022391

Table 5.

Predictors for major amputation.

Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age (yr) 0.99 (0.96–1.03) .721
Gender (Male vs Female) 0.84 (0.29–2.43) .751
Current smoking 1.02 (0.13–7.79) .986
Current dialysis 4.07 (1.36–12.21) .012 2.30 (0.75–7.10) .146
Chronic kidney disease 3.30 (0.92–11.85) .067
Hemoglobin 0.65 (0.46–0.91) .014 0.68 (0.47–0.99) .047
Rutherford classification (6 vs 5) 4.87 (1.09–21.78) .038 1.36 (0.29–6.45) .698
University of Texas classification
 Grade 1 as reference
 Grade 2 3.00 (0.27–33.09) .370
 Grade 3 13.05 (1.68–101.20) .014
Infection 12.07 (1.58–92.27) .016 11.78 (1.40–98.95) .023
Occluded plantar arch 1.60 (0.56–4.57) .378
Run-off vessel number after EVT 0.87 (0.42–1.78) .693
Prostaglandin E1 use 0.20 (0.03–1.53) .121
Femoropopliteal drug-coating balloon 0.43 (0.06–3.26) .412
Infra-popliteal drug-coating balloon 0.38 (0.05–2.92) .353
Mean pre-EVT temperature of whole foot 1.08 (0.90–1.29) .409
Mean post-EVT temperature of whole foot 0.98 (0.82–1.16) .795
DIFF1 0.91 (0.79–1.06) .229
DIFF2 0.50 (0.31–0.83) .007 0.51 (0.27–0.98) .045