Table 2.
The baseline demographics and tumor features of non-functional pancreatic neuroendocrine neoplasms in the present study.
| Patients, No. (%) | ||||
| Factor | G1/G2 NF-p-NETs(N = 152) | G3 NF-p-NECs(N = 78) | NF-p-NENs(N = 230) | P valueA |
| Patients gender | .436 | |||
| Male | 70 (46.1) | 48 (61.5) | 118 (51.3) | |
| Female | 82 (53.9) | 30 (38.5) | 112 (48.7) | |
| Age at diagnosis, yr | .018 | |||
| Median | 49.0 | 61.2 | 53.4 | |
| Range | 14.0–78.3 | 17.4–86.7 | 14.0–86.7 | |
| Clinical symptoms | .685 | |||
| Abdominal pain | 70 (46.1) | 50 (64.1) | 120 (52.2) | |
| Abdominal mass | 61 (40.1) | 42 (53.8) | 103 (44.8) | |
| Jaundice | 26 (17.1) | 38 (48.7) | 64 (27.8) | |
| Bleeding | 8 (5.3) | 14 (17.9) | 22 (9.6) | |
| Incidental diagnosis | 38 (24.0) | 28 (35.9) | 66 (28.7) | .112 |
| Tumor location | .097 | |||
| Head/uncinate | 76 (50.0) | 50 (64.1) | 126 (54.8) | |
| Body/tail | 76 (50.0) | 28 (35.9) | 104 (45.2) | |
| Tumor size | .041 | |||
| Median, cm | 2.5 | 4.0 | 3.5 | |
| Range, cm | 0.5–4.2 | 1.5–7.5 | 0.5–7.5 | |
| <2cm | 62 (40.8) | 20 (25.6) | 82 (35.6) | |
| 2cm≤ and <4cm | 38 (25.0) | 27 (34.6) | 65 (28.3) | |
| ≥4cm | 52 (34.2) | 31 (39.8) | 83 (36.1) | |
| Local lymph metastases | .136 | |||
| No | 114 (75.0) | 40 (51.3) | 154 (66.9) | |
| Yes, No.≤3 | 18 (11.8) | 12 (15.4) | 30 (13.1) | |
| Yes, No.>3 | 20 (13.2) | 26 (33.3) | 46 (20.0) | |
| Distant metastasis | 19 (12.5) | 18 (23.1) | 37 (16.1) | .323 |
| US-guided-FNA | 20 (13.2) | 14 (17.9) | 34 (14.8) | .962 |
| Surgical procedure | .158 | |||
| LRP | 38 (25.0) | 15 (19.2) | 53 (23.0) | |
| DP | 62 (40.8) | 23 (29.5) | 85 (37.0) | |
| PD | 42 (27.6) | 24 (30.8) | 66 (28.7) | |
| BPB | 10 (6.7) | 16 (20.5) | 26 (11.3) | |
| Radical resectionC | 136 (89.5) | 54 (69.2) | 190 (82.6) | .085 |
| Medical therapyD | 48 (31.6) | 20 (25.6) | 68 (29.6) | .159 |
| Patient out of contact | 39 (25.7) | 8 (10.3) | 47 (20.4) | .284 |
| Dead at follow-up | 50 (32.9) | 37 (47.4) | 87 (37.8) | .089 |