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. 2020 Nov 2;20(12):1–134.

Table 11:

Scenario Analysis Results

Home Versus Outpatient Clinic NB-UVB
Incremental Costa (95% CrI) Incremental QALYsb (95% CrI) ICER ($/QALY)
Reference case $4,509 ($3,365–$5,714) 0.29 (−0.24 to 0.81) 15,675
1. Cost perspective: societal −$5,271 (−$9,356 to −$1,416) 0.29 (−0.24 to 0.81) Outpatient clinic NB-UVB is dominated (more costly, less effective) by home NB-UVB
2. Cost perspective: societal and remote outpatients (higher switching out of outpatient clinic NB-UVB) −$10,212 (−$13,069 to −$7,485) 0.67 (0.31–1.03) Outpatient clinic NB-UVB is dominated (more costly, less effective) by home NB-UVB
3. Number of treatments for outpatients: 51 $3,587 ($2,351–$4,860) 0.29 (−0.24 to 0.81) 12,600
4. Cost of home NB-UVB device: rental-purchase $3,038 ($1,936–$4,220) 0.29 (−0.24 to 0.81) 10,563
5. Cost of home NB-UVB device: mixed home phototherapy devices $2,781 ($1,905–$3,697) 0.29 (−0.24 to 0.81) 9,669
6. Cost of home NB-UVB device with 75% of cost covered by the public payer
  • A.

    Purchased outright

 $3,063 ($2,158–$4,005) 0.29 (−0.24 to 0.81) 10,648
  • B.

    Rental-purchase

 $1,960 ($1,075–$2,878) 0.29 (−0.24 to 0.81) 6,814
7. Transition probabilities for home NB-UVB
  • A.

    Home NB-UVB has higher switching compared to outpatient clinic NB-UVB (worse adherence)

 $4,170 ($3,095–$5,293) −0.17 (−0.58–0.26) Home NB-UVB is dominated (more costly, less effective) by outpatient clinic NB-UVB
  • B.

    Home NB-UVB has equal switching compared to outpatient clinic NB-UVB (equal adherence)

 $4,379 ($3,292–$5,555) 0.11 (−0.12–0.33) 38,424
  • C.

    Home NB-UVB has much lower switching compared to outpatient clinic NB-UVB (better adherence)

 $4,639 ($3,484–$5,868) 0.46 (0–0.93) 10,032
8. Cost of topical therapy: more expensive treatment $3,835 ($1,791–$5,889) 0.29 (−0.24 to 0.81) 13,334
9. Treatment pathway include systemic non-biologics, biologic, and topical therapy $2,398 (−$3,780–$8,212) 0.27 (−0.21 to 0.75) 8,877
10. Utilities of NB-UVB calculated using PASI scores $4,509 ($3,365–$5,714) 0.12 (−1.23 to 1.44) 36,691
11. Time horizon
  5 years $4,264 ($3,255–$5,338) 0.15 (−0.07 to 0.37) 28,889
  15 years $4,671 ($3,383–$6,038) 0.39 (−0.45 to 1.22) 11,917
12. Discounting
  0% $4,550 ($3,384–$5,793) 0.31 (−0.26 to 0.88) 14,674
  3% $4,471 ($3,348–$5,649) 0.27 (−0.21 to 0.75) 16,711

Abbreviations: CrI, credible interval; ICER, incremental cost-effectiveness ratio; NB-UVB, narrowband ultraviolet B phototherapy; PASI, Psoriasis Area and Severity Index; QALY, quality-adjusted life year.