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. 2020 Nov 16;15(11):e0242254. doi: 10.1371/journal.pone.0242254

Table 3. Trend of glomerular filtration rate over time (in mL/min/1.73m2/yr) for all patients.

ALL PATIENTS
n = 151
Overall trend over time -2.99 ± 0.16
Trend during the pre- and post-dialysis initiation periods PRE POST CHANGE
Value (95% CI) P value
Unadjusted model -3.90 ± 0.32 -2.71 ± 0.18 +1.19 (0.48–1.90) 0.001
Adjusted for treatment group model -4.09 ± 0.33 -2.69 ± 0.18 +1.40 (0.68–2.12) <0.001
Exploratory model* -4.10 ± 0.33 -2.69 ± 0.18 +1.41 (0.67–2.14) <0.001

*Adjusted for patients’ characteristics at enrollment: treatment group (early- vs. late-start), age, sex, ethnicity (Caucasian vs non-Caucasian), initial dialysis dose (incremental vs full), presence of diabetes mellitus and history of cardiovascular disease.