Table 4. Trend of glomerular filtration rate over time (in mL/min/1.73m2/yr) in the early and late dialysis start groups.
| EARLY-START GROUP | LATE-START GROUP | |||||||
|---|---|---|---|---|---|---|---|---|
| n = 79 | n = 72 | |||||||
| Overall trend over time | -2.93 ± 0.26 | -3.05 ± 0.17 | ||||||
| Trend during the pre- and post-dialysis initiation periods | PRE | POST | CHANGE | PRE | POST | CHANGE | ||
| Value (95% CI) | P value | Value (95% CI) | P value | |||||
| Unadjusted model | -4.55 ± 0.68 | -2.71 ± 0.28 | +1.84 (0.43–3.25) | <0.001 | -4.08 ± 0.39 | -2.50 ± 0.19 | +1.58 (0.69–2.46) | <0.001 |
| Exploratory model* | -4.68 ± 0.71 | -2.71 ± 0.28 | +1.97 (0.50–3.44) | 0.008 | -4.07 ± 0.39 | -2.49 ± 0.19 | +1.58 (0.70–2.46) | <0.001 |
*Adjusted for patients’ characteristics at enrollment: age, sex, ethnicity (Caucasian vs non-Caucasian), initial dialysis dose (incremental vs full), presence of diabetes mellitus and history of cardiovascular disease.