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The significance classes represent the quality of the measurement and are defined in accordance with the different shape of the dose-response curve (CURVE CLASS2).37
| CURVE CLASS2 | SIGNIFICANCE CLASS |
|---|---|
| 1.1 1.2 2.1 2.2 | HIGH |
| 1.3 1.4 2.3 3.4 | MODERATE |
| 3 | LOW |
| 4 | INACTIVEa |
| 5 | INCONCLUSIVE |
A type 4 curve is a flat curve, which indicates that the compound does not show any activity.
