Table 2. Description of Disease and Treatment.
| Parent study (N = 96), total (%) | Not in current study (N = 40), total (%) | In current study (N = 56), total (%) | p value | |
|---|---|---|---|---|
| Type of cancer | .517 | |||
| Squamous cell carcinoma | 81 (84.4) | 33 (82.5) | 48 (84.9) | |
| Other | 15 (15.6) | 7 (17.5) | 8 (14.3) | |
| Location of cancer | .427 | |||
| Oral cavity | 20 (20.8) | 9 (22.5) | 11 (19.6) | |
| Oropharynx | 41 (42.7) | 13 (32.5) | 28 (50.0) | |
| Larynx | 13 (13.5) | 8 (20.0) | 5 (8.9) | |
| Other | 22 (22.9) | 10 (25.0) | 9 (16.1) | |
| Known viral etiology | .039 | |||
| None | 51 (53.1) | 25 (62.5) | 26 (46.4) | |
| HPV | 28 (29.2) | 5 (12.5) | 23 (41.1) | |
| Other | 17 (17.7) | 10 (25.0) | 7 (12.5) | |
| Surgery | .422 | |||
| Yes | 41 (42.7) | 19 (47.5) | 22 (39.4) | |
| No | 55 (57.3) | 21 (52.5) | 34 (60.7) | |
| Chemotherapy | .227 | |||
| Yes | 94 (97.9) | 40 (100) | 54 (96.4) | |
| No | 2 (2.1) | 0 (0) | 2 (3.6) | |
| Type of surgery | (N = 41) | (N = 19) | (N = 22) | .764 |
| RND | 2 (4.9) | 1 (5.3) | 1 (4.6) | |
| Modified ND | 25 (61.0) | 10 (52.6) | 15 (68.2) | |
| Total/Partial laryngectomy | 4 (9.8) | 3 (15.8) | 1 (4.6) | |
| Other | 10 (24.4) | 5 (26.3) | 5 (22.7) | |
| Concurrent radiation | .239 | |||
| Yes | 94 (97.9) | 38 (100) | 54 (96.4) | |
| No | 2 (2.1) | 0 (0) | 2 (3.6) | |
| PEG | .078 | |||
| Yes | 49 (52.1) | 24 (63.2) | 25 (44.6) | |
| No | 45 (47.9) | 14 (36.8) | 31 (55.4) | |
| Type of treatment | .380 | |||
| Chemo XRT | 15 (16.0) | 7 (18.4) | 8 (14.3) | |
| Induction + chemo XRT | 42 (44.7) | 14 (36.8) | 28 (50.0) | |
| Surgery + chemo XRT | 25 (26.6) | 11 (28.9) | 14 (25.0) | |
| Surgery + radiotherapy | 2 (2.1) | 0 (0) | 2 (2.1) | |
| Induction + chemo XRT + surgery | 10 (10.6) | 6 (15.8) | 4 (7.1) | |
| Distant metastasis | .445 | |||
| Yes | 5 (5.2) | 3 (7.5) | 2 (3.6) | |
| No | 91 (94.8) | 37 (92.5) | 54 (96.4) | |
| Tumor TNM stage | .317 | |||
| Stage 0–3 | 45 (46.9) | 20 (50.0) | 25 (44.6) | |
| Stage 2a, 2b, 2c, 3b | 51 (53.1) | 20 (50.0) | 31 (55.4) | |
| Stage of tumor | .849 | |||
| Stage 1–3 | 26 (27.1) | 11 (27.5) | 15 (26.8) | |
| Stage 4a and 4b | 70 (72.9) | 29 (72.5) | 41 (73.2) | |
| Size of tumor | .259 | |||
| 3 or less | 67 (68.8) | 23 (57.5) | 44 (76.8) | |
| 4 | 12 (12.5) | 9 (22.5) | 3 (5.4) | |
| 4a/b | 11 (11.4) | 5 (12.5) | 6 (10.7) | |
| X | 6 (6.3) | 3 (7.5) | 3 (5.4) |
Note. HPV = human papillomavirus; PEG = percutaneous endoscopic gastrostomy; RND = radical neck dissection; ND = neck dissection; XRT = radiation.