Table 2. Analysis of 5-year overall and event-free survival according to different demographic, histological, and clinical variables of pediatric patients with medulloblastoma treated in a Brazilian reference center (n=106), Campinas, São Paulo.
| Total cases | 5-year overall survival rate (%) | p-value* | 5-year event-free survival rate (%) | p-value* | |
|---|---|---|---|---|---|
| Age group (years) | |||||
| <3 | 15 | 60.0 | 0.731 | 53.3 | 0.663 |
| 3-16 | 87 | 69.0 | 62.1 | ||
| >16 | 4 | 75.0 | 50.0 | ||
| Gender | |||||
| Female | 36 | 75.0 | 0.395 | 66.7 | 0.533 |
| Male | 70 | 64.3 | 57.1 | ||
| Surgery | |||||
| Complete | 67 | 68.7 | 0.026 | 61.2 | 0.12 |
| Incomplete | 36 | 55.6 | 52.8 | ||
| Biopsy | 3 | 33.3 | 33.3 | ||
| Histology | |||||
| Classic | 67 | 61.2 | 0.070 | 53.7 | 0.128 |
| Desmoplastic | 29 | 86.2 | 75.9 | ||
| A/LC | 10 | 60.0 | 60.0 | ||
| Metastasis | |||||
| Present | 42 | 59.5 | 0.183 | 52.4 | 0.231 |
| Absent | 64 | 73.4 | 65.6 | ||
| Risk | |||||
| High | 64 | 59.4 | 0.029 | 51.6 | 0.028 |
| Standard | 42 | 81.0 | 3.8 | ||
*Log-rank test; A/LC: anaplastic/large cells.