Table 3. Association between molecular subtypes and demographic, histological, and metastasis at diagnosis data from 49 patients and analysis of 5-year overall and event-free survival.
| WNT | SHH | Non-WNT/non-SHH | p-value* | |
|---|---|---|---|---|
| Gender | ||||
| Female | 5 | 4 | 7 | 0.134 |
| Male | 3 | 13 | 17 | |
| Age (years) | ||||
| <3 | 0 | 7 | 1 | 0.005 |
| 3-16 | 8 | 10 | 23 | |
| >16 | 0 | 0 | 0 | |
| Histology | ||||
| Classic | 5 | 5 | 19 | 0.008 |
| Desmoplastic | 2 | 11 | 4 | |
| A/LC | 1 | 1 | 1 | |
| Metastasis | ||||
| Present | 2 | 4 | 17 | 0.005 |
| Absent | 6 | 13 | 7 | |
| Overall survival** (%) | 75 | 58.8 | 66.7 | 0.762 |
| Event-free survival**(%) | 75 | 52.9 | 41.7 | 0.547 |
*Fisher’s exact test; **Log-rank test; WNT: wingless; SHH: sonic hedgehog; A/LC: anaplastic/large cells.