Figure 1.

Model-based vs observed distributions of race, education, FHLC, and COPD for the 1950 birth cohort (male and female combined). The distributions of the remaining risk factors and the bivariate distributions of risk factors are shown in Supplementary Figures 4 and 5 (available online). Data sources: Race and education data from US Census Bureau; FHLC and COPD from the 2000 NHIS. We note that the risk factor simulator algorithm was calibrated to these reference data (see Supplementary Methods, available online). COPD = chronic obstructive pulmonary disease; FHLC = family history of lung cancer; LC = lung cancer; NHIS = National Health Interview Survey.