Table 4:
Weighted Outcomes for Patients with an Adequate Trial of an Effective Medication for PTSD plus PCL Measurement
| Fluoxetine (n=228) | Paroxetine (n=87) | Sertraline (n=307) | Topiramate (n=96) | Venlafaxine (n=116) |
|---|---|---|---|---|
| 58.5 (11.7) | 58.4 (11.3) | 57.5 (10.9) | 58.3 (15.0) | 58.6 (11.8) |
| −8.1 (15.0) | −6.8 (16.0) | −7.5 (12.2) | −6.8 (14.0) | −10.1 (19.5) |
| 2.9 (8) | 0.0 (0) | 4.7 (14) | 1.3 (2) | 10.9 (9) |
| 14.4 (3.6) | 14.4 (3.6) | 14.3 (3.8) | 15.1 (3.5) | 14.3 (3.9) |
| −1.8 (4.2) | −1.6 (4.9) | −1.8 (3.6) | −1.8 (4.5) | −2.1 (5.2) |
| 6.5 (1.5) | 6.3 (1.8) | 6.3 (1.6) | 6.4 (1.8) | 6.2 (1.9) |
| −1.1 (2.4) | −0.8 (2.2) | −0.7 (1.8) | −0.7 (2.9) | −1.0 (2.6) |
| 19.9 (4.6) | 19.5 (5.6) | 19.4 (5.2) | 19.5 (6.0) | 20.6 (5.3) |
| −2.8 (6.2) | −2.4 (6.2) | −2.5 (5.1) | −2.2 (5.5) | −4.2 (7.6) |
| 17.4 (3.9) | 17.9 (3.8) | 17.3 (3.9) | 17.2 (7.1) | 17.2 (4.7) |
| −2.5 (5.2) | −2.1 (5.6) | −2.5 (4.0) | −2.1 (5.1) | −2.8 (6.2) |
| 6.0 (1.8) | 6.1 (1.6) | 6.2 (1.7) | 6.3 (1.9) | 6.1 (1.8) |
| −0.7 (2.1) | −0.8 (2.3) | −1.1 (1.8) | −0.9 (2.3) | −0.9 (2.7) |
*
Significant Differences are assessed at p<0.05 for the Omnibus comparison, with pair-wise testing where indicated.
Abbreviations. PTSD=Posttraumatic Stress Disorder, PCL=PTSD Checklist, NACM=Negative Alterations in Cognitions and Mood