Table 2.
Parameters | Group 1 without HF (n = 20) Me [25; 75] | Group 2 HFpEF (n = 29) Me (25, 75) | Group 3 HFmrEF (n = 13) Me (25, 75) | p value | |||
---|---|---|---|---|---|---|---|
(1 vs. 2 vs. 3) | (1 vs. 2) | (1 vs. 3) | (2 vs. 3) | ||||
EF (Simpson), % | 61 (59, 65) | 61 (57, 62) | 46 (41, 48) | <0.001 | 0.12 | <0.001 | <0.001 |
LA dimension, mm | 43 (40, 47) | 41 (38, 47) | 44 (40, 50) | 0.29 | 0.34 | 0.22 | 0.21 |
LA volume index, ml/m2 | 33.5 (30.0, 38.7) | 42.0 (37.1, 46.4) | 48.3 (38.0, 59.0) | <0.001 | 0.003 | <0.001 | 0.23 |
E/e'avg | 7 (8, 9) | 11 (9, 13) | 11 (9, 14) | 0.006 | 0.009 | 0.005 | 0.4 |
PAP, mmHg | 26 (19, 30) | 24 (18-29) | 26 (20-31) | 0.57 | 0.37 | 0.61 | 0.18 |
LV dimension, mm | 49 (46, 53) | 47 (45, 51) | 50 (46, 52) | 0.4 | 0.49 | 0.43 | 0.13 |
EDV, ml | 111 (94.7, 126.7) | 117 (102, 135) | 167 (125, 220) | 0.025 | 0.21 | 0.005 | 0.007 |
LV volume index, ml/m2 | 50 (45, 63) | 59 (49, 68) | 66 (59, 74) | 0.08 | 0.13 | 0.03 | 0.037 |
ESV, ml | 46 (34, 53) | 45 (39, 61) | 89 (61, 134) | 0.007 | 0.35 | 0.001 | 0.002 |
IVS, mm | 10 (9, 11) | 11 (10, 13) | 11.5 (11, 13) | 0.24 | 0.56 | 0.39 | 0.85 |
PW, mm | 11 (10, 12) | 11 (10, 13) | 11 (9, 12) | 0.51 | 0.43 | 0.53 | 0.41 |
RWT | 0.44 (0.41, 0.46) | 0.53 (0.49, 0.57) | 0.52 (0.5, 0.55) | 0.009 | 0.007 | 0.01 | 0.77 |
LVMM, g | 197 (177, 244) | 252 (207, 335) | 271 (228, 401) | 0.01 | 0.07 | 0.034 | 0.28 |
LVM/BSA, g/m2 | 105 (91, 119) | 118 (94, 142) | 155 (97, 196) | 0.023 | 0.27 | 0.02 | 0.17 |
LVM/height, g/m | 116 (109, 131) | 177 (156.0, 192.8) | 205.7 (160.1, 220.6) | 0.002 | 0.02 | 0.001 | 0.043 |
LVM/height, g/m2.7 | 49 (42, 56) | 52.5 (46.6, 75.1) | 69.2 (52.6, 89.3) | 0.04 | 0.15 | 0.01 | 0.08 |
GLS avg, % | -19 (-17, -20) | -19(-17, -20) | -16.5(-14, -19.0) | 0.016 | 0.91 | 0.041 | 0.041 |
EF: ejection fraction; LV: left ventricle; ESV: end-systolic volume of the left ventricle; EDV: end-diastolic volume of the left ventricle; LVM: left ventricular myocardial mass; LA: left atrium; IVS: interventricular septum; PW: posterior wall of left ventricle; RWT: relative wall thickness of the left ventricle; BSA: body surface area.