Table 2. CSF biomarker cutoff values that best discriminate ADD from NC.

CSF biomarker	Cutoff	AUC	Sensitivity, %	Specificity, %
Aβ42, pg/mL	667.9	0.960	97	88
T-tau, pg/mL	355.3	0.918	73	96
P-tau, pg/mL	61.8	0.684a,b	59	82
T-tau/Aβ42	0.641	0.994b,c	97	98
P-tau/Aβ42	0.103	0.963b,c,d	92	94

CSF = cerebrospinal fluid, ADD = Alzheimer's disease dementia, NC = normal control, AUC = area under curve, Aβ42 = beta amyloid 1-42, T-tau = total tau, P-tau = phosphorylated tau.

^aP <0.05 compared to AUC of the model for Aβ42; ^bP <0.05 compared to AUC of the model for T-tau; ^cP <0.05 compared to AUC of the model for P-tau; ^dP <0.05 compared to AUC of the model for T-tau/Aβ42.