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. 2020 Nov 12;13:591–599. doi: 10.2147/PGPM.S278897

Table 5.

Interactions Between Gene and Environmental Factors Analysis

Gene Environment Case Control OR (95% CI) Reflecting Information
AA/GG Smoking
152 137 1.00 E (-), the role of G
- + 73 34 1.94 (1.21–3.09) E (+), the role of G
+ - 17 36 0.43 (0.23–0.79) G (-), the role of E
+ + 6 9 0.60 (0.21–1.73) G (+), the role of E
GA/GG Smoking
- - 152 137 1.00 E (-), the role of G
- + 73 34 1.94 (1.21–3.09) E (+), the role of G
+ - 48 77 0.56 (0.37–0.86) G (-), the role of E
+ + 24 27 0.80 (0.44–1.45) G (+), the role of E
AA/GG Drinking
- - 143 130 1.00 E (-), the role of G
- + 82 41 1.82 (1.17–2.83) E (+, the role of G
+ - 13 32 0.37 (0.19–0.73) G (-), the role of E
+ + 10 13 0.70 (0.30–1.65) G (+), the role of E
GA/GG Drinking
- - 143 130 1.00 E (-), the role of G
- + 82 41 1.82 (1.17–2.83) E (+), the role of G
+ - 49 83 0.54 (0.35–0.82) G (-), the role of E
+ + 23 21 1.00 (0.53–1.88) G (+), the role of E
AA/GG BMI
- - 175 125 1.00 E (-), the role of G
- + 50 46 0.78 (0.49–1.23) E (+), the role of G
+ - 16 41 0.28 (0.15–0.52) G (-), the role of E
+ + 7 4 1.25 (0.36–4.36) G (+), the role of E
GA/GG BMI
- - 175 125 1.00 E (-), the role of G
- + 50 46 0.78 (0.49–1.23) E (+), the role of G
+ - 51 41 0.89 (0.55–1.42) G (-), the role of E
+ + 21 30 0.50 (0.27–0.91) G (+), the role of E
AA/GG Hypertension
- - 151 128 1.00 E (-), the role of G
- + 74 43 1.46 (0.94–2.27) E (+), the role of G
+ - 17 32 0.45 (0.24–0.85) G (-), the role of E
+ + 16 13 1.04 (0.48–2.25) G (+), the role of E
GA/GG Hypertension
- - 151 128 1.00 E (-), the role of G
- + 74 43 1.46 (0.94–2.27) E (+), the role of G
+ - 45 81 0.47 (0.31–0.73) G (-), the role of E
+ + 27 23 1.00 (0.54–1.82) G (+), the role of E