Table 5.

Cox Proportional Hazard Models on PFS of NPC Patients

	Univariate			Multivariate
	HR	95% CI	P value	HR	95% CI	P value
Age, year (<46 vs ≥46)	1.49	0.86–2.58	0.159
Sex (male vs female)	0.40	0.19–0.86	0.018*	0.41	1.38–6.33	0.039*
Smoking (Yes vs No)	0.52	0.30–0.90	0.019*	1.42	0.77–2.63	2.265
Alcohol taking (Yes vs No)	1.66	0.93–2.97	0.090
Clinical stage (I–II vs III–IV)	3.12	1.33–7.33	0.009*	0.66	0.18–2.45	0.534
T stage (T1-2 vs T3-4)	2.38	1.34–4.23	0.003*	3.15	1.35–7.36	0.007*
N stage (N0-1 vs N2-3)	2.83	1.51–5.30	0.001*	2.55	1.29–5.02	0.008*
M stage (M0 vs M1)	1.25	0.17–9.14	0.828
CD163 density (low vs high)	1.81	1.03–3.17	0.038*	1.23	0.67–2.26	0.513
CD68 density (low vs high)	1.02	0.59–1.76	0.952
PD-L1 (negative vs positive)	0.80	0.46–1.38	0.416

Note: *p<0.05.