Table 6.

Cox Proportional Hazard Models on OS of NPC Patients

	Univariate			Multivariate
	HR	95% CI	P value	HR	95% CI	P value
Age, year (<46 vs ≥46)	1.50	0.89–2.53	0.128
Sex (male vs female)	0.76	0.41–1.38	0.363
Smoking (Yes vs No)	1.36	0.81–2.29	0.239
Alcohol taking (Yes vs No)	1.26	0.71–2.24	0.430
Clinical stage (I–II vs III–IV)	4.15	1.66–10.39	0.002*	1.70	0.48–6.03	0.412
T stage (T1-2 vs T3-4)	2.38	1.34–4.23	0.003*	1.61	0.78–3.30	0.196
N stage (N0-1 vs N2-3)	2.58	1.49–4.48	0.001*	1.752	0.90–3.42	0.101
M stage (M0 vs M1)	9.88	4.61–21.16	<0.001*	6.01	2.66–13.57	<0.001*
CD163 density (low vs high)	1.94	1.13–3.31	0.016*	1.07	0.59–1.94	0.818
CD68 density (low vs high)	1.17	0.68–1.96	0.555
PD-L1 (negative vs positive)	0.75	0.45–1.26	0.279

Note: *p<0.05.