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. Author manuscript; available in PMC: 2021 May 15.
Published in final edited form as: Cancer Res. 2020 Sep 24;80(22):5051–5062. doi: 10.1158/0008-5472.CAN-20-1453

Fig. 5. FGFR1-dependent SCLC cells activated PLCG1 require activation of PLCG1.

Fig. 5.

(A) Immunoblot for phosphorylated forms and respective total protein in control and Fgfr1-preSC. ACTB blot verifies equal loading of total proteins. (B) Representative images of soft agar colonies formed from human SCLC lines with FGFR1 knockdown (top) and quantification of colonies >0.2mm in diameter (bottom) (n=3 replicates per cell type). (C, D) Immunoblots for cleaved/total CASP3 and phosphorylated/total proteins of PLCG1, ERK1/2, AKT, and STAT1 in human SCLC lines with FGFR1 knockdown. Scale bar: 5mm.