Table 4.

Results from multiple regression analysis and relative contribution of predictors of verbal memory performance in BIM Study participants using total memory complaints.

	Verbal memory performance
Predictor	Regression coefficients (SE)	p-value	Pratt indexa (%)	Model R2 (%)
Age	−0.041 (0.009)	<0.001	18.1	36.4b
Sex	−0.641 (0.101)	<0.001	40.3
NAART	0.024 (0.007)	0.001	13.5
CVC 65W	−0.971 (0.346)	0.005	2.6
Total memory complaints	−0.293 (0.128)	0.023	5.4
Depression	−0.003 (0.008)	0.723	0.5
APOE	−0.082 (0.110)	0.454	1.2
BIN1	0.329 (0.100)	0.001	8.0
CLU	−0.308 (0.141)	0.030	5.2
CR1	0.053 (0.105)	0.616	0
PICALM	−0.470 (0.172)	0.007	5.1
Age	−0.035 (0.008)	<0.001	15.1	35.5c
Sex	−0.715 (0.108)	<0.001	41.1
NAART	0.025 (0.008)	0.001	13.4
$\overline{V}\text{P}$ 65 W	−0.338 (0.153)	0.029	0
Total memory complaints	−0.286 (0.129)	0.028	5.9
Depression	−0.003 (0.008)	0.713	1.7
APOE	−0.082 (0.110)	0.459	2.3
BIN1	0.332 (0.101)	0.002	8.2
CLU	−0.306 (0.142)	0.033	5.8
CR1	0.068 (0.106)	0.518	1.2
PICALM	−0.432 (0.173)	0.014	5.4

Note. APOE, apolipoprotein E; BIM, Brain in Motion; BIN1, bridging integrator 1; CLU, clusterin; CR1, complement receptor 1; CVC, cerebrovascular conductance (cm·s⁻¹/mmHg); NAART, North American Adult Reading Test; PICALM, phosphatidylinositol-binding clathrin assembly protein; $\overline{V}\text{P}$, maximum peak systolic blood flow velocity (cm·s⁻¹/mmHg). ^aThe Pratt index describes the contribution of each independent variable to the variance in the dependent variable rounded to the nearest tenth. ^bCoefficient of multiple determination: R² = 0.364; F_(11,214) = 11.120; p < 0.001. ^cCoefficient of multiple determination: R² = 0.355; F_(11,214) = 10.702; p < 0.001.