Table 1.
Demographic and clinical characteristics of PD patients.
| PIGD | TD | Intermediate | P | P* | |
|---|---|---|---|---|---|
| Subject, n (%) | 51 (50.5) | 33 (32.7) | 17 (16.8) | ||
| Gender, F/M | 26/25 | 19/14 | 7/10 | 0.544a | 0.554a |
| Age, mean ± SD | 66.3 ± 8.0 | 63.1 ± 8.7 | 66.1 ± 9.2 | 0.213b | 0.086b |
| Age at onset, mean ± SD | 61.2 ± 8.6 | 59.0 ± 9.0 | 62.8 ± 9.2 | 0.314b | 0.262b |
| Duration, years (IR) | 5.0 (2.0–7.0) | 3.0 (1.0–6.0) | 3.0 (1.0–5.0) | 0.060c | 0.068d |
| UPDRS-Total, mean ± SD | 34.3 ± 16.4 | 22.5 ± 12.9 | 21.5 ± 9.0 | <0.001b | 0.001b |
| UPDRS-III, mean ± SD | 19.3 ± 10.9 | 14.4 ± 8.7 | 12.5 ± 5.5 | 0.013b | 0.034b |
| H-Y stage, median (IR) | 2.5 (2.0–2.5) | 2.0 (1.0–2.0) | 2.0 (1.0–2.0) | <0.001c | 0.002d |
| LEDD, mg (IR) | 450.0 (300.0–601.2) | 375.6 (275.0–550.0) | 450.0 (350.0–601.2) | 0.589c | 0.452d |
| NMSS, median (IR) | 52.0 (33.0–65.0) | 17.0 (12.0–29.5) | 27.0 (17.5–40.5) | <0.001c | <0.001d |
| SCOPA-AUT | 13.9 ± 6.3 | 7.5 ± 4.7 | 9.3 ± 5.6 | <0.001b | <0.001b |
| OH, n (%) | 20 (39.2) | 3 (9.1) | 5 (29.4) | 0.011a | 0.006a |
| Absent SSR, n (%)e | 37 (18.1) | 6 (4.5) | 9 (13.2) | 0.001a | <0.001a |
H-Y, Hoehn and Yahr; IR, interquartile range; LEDD, L-dopa equivalent daily dosage; NMSS, non-motor symptom assessment scale; OH, orthostatic hypotension; PD, Parkinson's disease; PIGD, postural instability and gait disturbance; SCOPA-AUT, scales for outcomes in PD-autonomic symptoms; SD, standard deviation; SSR, sympathetic skin response; TD, tremor-dominant; UPDRS, unified Parkinson's disease rating scale.
Compared between the PIGT and TD subtypes.
Analyzed by Chi square test.
Analyzed by one-way analysis of variance.
Analyzed by Kruskal-Wallis test.
Analyzed by Mann-Whitney test.
n and % represent the affected limb number and its percentage relative to the total limb number, respectively.