Table 1.
CPPC study demographic and patient characteristics.
| Males [N] | Females [N] | Total [N] | F/M | P-value | |
|---|---|---|---|---|---|
| CPPC | |||||
| EM | 18 | 245 | 263 | 2.3x | < 0.01 |
| TMD | 10 | 162 | 172 | 2.7x | < 0.01 |
| IBS | 20 | 201 | 221 | 1.7x | 0.02 |
| FM | 2 | 94 | 96 | 7.8x | < 0.01 |
| VVS | 0 | 100 | 100 | N/A | N/A |
| ANY | 30 | 342 | 372 | 1.9x | < 0.01 |
| CTL | 57 | 180 | 237 | 0.5x | < 0.01 |
| # CPPCs | |||||
| 0 | 57 | 180 | 237 | 0.5x | < 0.01 |
| 1 | 19 | 123 | 142 | 1.1x | 0.90 |
| 2 | 3 | 49 | 52 | 2.7x | 0.10 |
| 3 | 7 | 115 | 122 | 2.7x | < 0.01 |
| 4 | 1 | 39 | 40 | 6.5x | 0.04 |
| 5 | 0 | 16 | 16 | N/A | N/A |
| Ancestry | |||||
| Cauc | 55 | 366 | 421 | 1.1x | 0.53 |
| Af-Am | 25 | 117 | 142 | 0.8x | 0.28 |
| Other | 7 | 39 | 46 | 0.9x | 0.83 |
| Age [y] | 34.6 (±11.9) | 36.2 (±11.6) | 36.0 (±11.6) | 1.05x | 0.61 |
| min/max | 18/61 | 18/64 | 18/64 | ||
| Counts | 87 | 522 | 609 |
Distribution of CPPCs and characteristics in males and in females. Participants can report more than one chronic pain conditions, therefore the counts in each sex is higher than the total number of individuals in the cohort. All P-values obtained using exact Fisher test, except for age, using Welch’s two-sample unequal variance. Complex persistent pain conditions were: episodic migraine, EM; temporomandibular disorders, TMD; irritable bowel syndrome, IBS; fibromyalgia, FM; vulvar vestibulitis, VVS; any of preceding, ANY; or controls, CTL. Number of CPPCs (#) in any study participant range from 0 to 5, inclusively. Ancestries were: Caucasians, Cauc; African-Americans, Af-Am; and others.