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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: DNA Repair (Amst). 2020 Aug 11;95:102948. doi: 10.1016/j.dnarep.2020.102948

Figure 2. Potential model for MDC1-mediated co-activation of AR and ERα.

Figure 2.

MDC1 has been shown to co-immunoprecipitate with both AR and ERα, and there is evidence that it plays a role in recruiting GCN5 to acetylate H3K9, resulting in increased transcription of p21 [38, 42].