Table 3:
A summary of the biodistribution values for 89Zr-scFv in two mouse strains. The data are reported as mean ± standard deviation, n = 4 mice per time point.
| Strain | C57Bl6/J | nu/nu | ||||
|---|---|---|---|---|---|---|
| Time (hr) |
0.5 | 1.5 | 2.5 | 0.5 | 1.5 | 2.5 |
| Blood | 1.92±0.1 | 0.85±0.1 | 0.49±0.1 | 1.24±0.1 | 0.52±0.07 | 0.35±0.04 |
| Liver | 1.41±0.1 | 1.15±0.05 | 1.37±0.1 | 1.11±0.1 | 0.95±0.09 | 0.96±0.09 |
| Kidneys | 1.75±0.6 | 0.63±0.5 | 2.06±0.8 | 0.54±0.4 | 0.79±0.5 | 1.15±0.1 |
| Spleen | 2.10±0.1 | 1.64±0.2 | 2.199±0.62 | 2.04±0.3 | 1.85±0.1 | 1.25±0.06 |
| Muscle | 0.47±0.05 | 0.36±0.05 | 0.16±0.02 | 0.62±0.1 | 0.38±0.03 | 0.54±0.2 |
| Bone | 0.62±0.06 | 0.50±0.1 | 0.52±0.2 | 0.98±0.04 | 0.89±0.2 | 0.60±0.04 |