Table 4:
Tumor to normal ratios over time for the 89Zr-minibody in two mouse backgrounds.
Strain | C57Bl6/J | nu/nu | ||||||
---|---|---|---|---|---|---|---|---|
Time (hr) | 2 | 8 | 24 | 48 | 2 | 8 | 24 | 48 |
Blood | 1.40±0.1 | 2.52±0.2 | 10.14±2.0 | 28.44±4.5 | 1.23±0.08 | 2.47±0.3 | 12.16±3.0 | 18.79±2.2 |
Liver | 1.25±0.5 | 1.84±0.7 | 1.69±0.8 | 1.04±0.3 | 1.51±0.07 | 1.36±0.4 | 1.05±0.1 | 0.79±0.5 |
Kidneys | 0.55±0.04 | 0.70±0.1 | 0.64±0.2 | 0.36±0.02 | 0.57±0.07 | 0.59±0.04 | 0.44±0.03 | 0.31±0.1 |
Spleen | 0.21±0.04 | 0.46±0.09 | 0.40±0.01 | 0.29±0.03 | 0.35±0.1 | 0.41±0.1 | 0.25±0.03 | 0.29±0.2 |
Muscle | 6.14±0.7 | 8.17±1.1 | 15.15±2.0 | 13.55±4.4 | 4.45±1.4 | 8.68±3.7 | 8.97±1.1 | 11.89±9.5 |
Bone | 1.25±0.1 | 1.51±0.1 | 2.21±0.1 | 1.51±0.4 | 1.22±0.5 | 1.68±0.4 | 1.35±0.09 | 1.45±1.2 |